DataElement
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longName Disease Primary Diagnosis NCI Thesaurus Text
shortName 14905521v1.00:14905524v1.00
definition A term describing the main condition for evaluation and treatment as captured in the Disease or Diagnosis (C2991) branch of the National Cancer Institute Thesaurus (NCIt) hierarchy tree.
context CRDC
origin CRDC:Cancer Research Data Commons
workflowStatus RELEASED
registrationStatus Standard
latestVersionIndicator Yes
beginDate 2024-04-23
endDate
changeDescription
administrativeNotes 5/18/26 Added updated IDC alt def, which references NCIt rather than WHO ICD-O, per U.Wagner Imaging submission xls. mr; 3/18/26 Added IDC Diagnosis alt name, CSI. mr; 5/22/25 Added addt'l alt name, alt def, per June 2025 GDC DD. sl; 5/21/25 Classified in GDC Candidate CSI, added alt name, def, per June 2025 GDC DD. sl; 4/17/25 Corrected typo in LN from 5/22/24 change of rep term from Name to Text. mr; 10/4/24 Added alt name and TCIA rec CDE's csi info. bf; 6/24/24 Released and upd RS to Standard; resolved by-ref PV tool semantics. jk; 5/22/24 Increased VD max len from 50 to 100; changed VD rep term from Name to Text per RR direction that this can be Term or Code. Source Data Value field set temporarily to 'Term' pending request to software team for new option of 'Code or Term'. mr; 4/23/24 created for CRDC DSS SN 3718 (Primary Diagnosis) enum by ref CDE request. jk
unresolvedIssues
deletedIndicator No
createdBy JKNABLE
dateCreated 2024-04-23
modifiedBy COLBERTM
dateModified 2026-05-18
DataElementConcept
publicId 14905521
version 1
longName Disease Primary Diagnosis
shortName 2404658v1.00:2475293v1.00
definition Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function.:Occurring first in time or sequence; original; of greatest rank or importance or value._The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
context CRDC
origin CRDC:Cancer Research Data Commons
workflowStatus RELEASED
registrationStatus Qualified
latestVersionIndicator Yes
beginDate 2024-04-23
endDate
changeDescription
administrativeNotes 6/24/24 Released and upd RS to Qualified; resolved by-ref PV tool semantics. jk 4/23/24 created for CRDC DSS SN 3617 (Primary Diagnosis). jk
unresolvedIssues
deletedIndicator No
createdBy JKNABLE
dateCreated 2024-04-23
modifiedBy JKNABLE
dateModified 2024-06-24
ObjectClass
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longName Diseases and Disorders
shortName C2991
definition A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.
context NCIP
origin NCI Thesaurus
workflowStatus RELEASED
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changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy PWEST
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Concepts
longName Disease or Disorder
conceptCode C2991
definition Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function.
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Property
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longName Primary Diagnosis
shortName C25251:C15220
definition Occurring first in time or sequence; original; of greatest rank or importance or value.:The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
context NCIP
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workflowStatus RELEASED
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changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
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Concepts
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definition Occurring first in time or sequence; original; of greatest rank or importance or value.
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definition The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
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primaryIndicator Yes
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ConceptualDomain
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definition Specification of human conditions relevant to cancer. This includes observations, test results, history, and other concepts relevant to characterization of human cancer-related conditions. Non-neoplastic conditions of interest are also included.
context NCIP
origin NCI Thesaurus
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changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
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definition The National Cancer Institute (NCI) reference terminology and ontology. NCI Thesaurus (NCIt) provides controlled terminology for clinical care, translational and basic research, public dissemination of information and associated administrative activities. NCIt is updated monthly to support precise coding of data based on the most recent developments in the cancer and biomedical research community. NCIt has rich textual and formal logic descriptions of biomedical concepts, including full text definitions, synonyms, a true is_a taxonomic structure, polyhierarchy, inferred partonomy, and other features that make it suitable for supporting accurate human understanding and complex computer processing. NCIt has been produced by NCI Enterprise Vocabulary Services (EVS) since 1997, and adopted since then for use by numerous federal agencies, standards development and research organizations._Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function._The words of something written.
context CRDC
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referenceTerminologyDataValueSource Term
dataType CHARACTER
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administrativeNotes 4/17/25 Corrected typo in LN caused by rep term change from Name to Text. mr; 6/24/24 Released and upd RS to Qualified; resolved by-ref PV tool semantics. jk; 5/22/24 Increased max len from 50 to 100; changed rep term from Name to Text per RR direction that this can be Term or Code. Source Data Value field set temporarily to 'Term' pending request to software team for new option of 'Code or Term'. mr; 5/17/24 Upd PV to be link to NCIt C2991.
unresolvedIssues
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changeDescription
administrativeNotes 3/4/25 Added alt VM names per RFC 26 CR 1. sl
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context NCIP
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changeDescription
administrativeNotes 3/4/25 Added alt VM names per RFC 26 CR 1. sl; 10/10/23 changed Long Name from "Not Stated" to match NCIt Preferred name and current caDSR concept Long Name of "Not Reported" per Brenda.Janice . LS
unresolvedIssues
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definition The National Cancer Institute (NCI) reference terminology and ontology. NCI Thesaurus (NCIt) provides controlled terminology for clinical care, translational and basic research, public dissemination of information and associated administrative activities. NCIt is updated monthly to support precise coding of data based on the most recent developments in the cancer and biomedical research community. NCIt has rich textual and formal logic descriptions of biomedical concepts, including full text definitions, synonyms, a true is_a taxonomic structure, polyhierarchy, inferred partonomy, and other features that make it suitable for supporting accurate human understanding and complex computer processing. NCIt has been produced by NCI Enterprise Vocabulary Services (EVS) since 1997, and adopted since then for use by numerous federal agencies, standards development and research organizations._Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function.
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definition The National Cancer Institute (NCI) reference terminology and ontology. NCI Thesaurus (NCIt) provides controlled terminology for clinical care, translational and basic research, public dissemination of information and associated administrative activities. NCIt is updated monthly to support precise coding of data based on the most recent developments in the cancer and biomedical research community. NCIt has rich textual and formal logic descriptions of biomedical concepts, including full text definitions, synonyms, a true is_a taxonomic structure, polyhierarchy, inferred partonomy, and other features that make it suitable for supporting accurate human understanding and complex computer processing. NCIt has been produced by NCI Enterprise Vocabulary Services (EVS) since 1997, and adopted since then for use by numerous federal agencies, standards development and research organizations._Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function._The words of something written.
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definition The National Cancer Institute (NCI) reference terminology and ontology. NCI Thesaurus (NCIt) provides controlled terminology for clinical care, translational and basic research, public dissemination of information and associated administrative activities. NCIt is updated monthly to support precise coding of data based on the most recent developments in the cancer and biomedical research community. NCIt has rich textual and formal logic descriptions of biomedical concepts, including full text definitions, synonyms, a true is_a taxonomic structure, polyhierarchy, inferred partonomy, and other features that make it suitable for supporting accurate human understanding and complex computer processing. NCIt has been produced by NCI Enterprise Vocabulary Services (EVS) since 1997, and adopted since then for use by numerous federal agencies, standards development and research organizations.
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definition Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function.
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publicId 11518160
version 1
longName CTDC (Clinical and Translational Data Commons)
context CRDC
workflowStatus RELEASED
registrationStatus Application
ClassificationSchemeItems
publicId 14413707
version 1
longName CTDC Model
context CRDC
workflowStatus RELEASED
registrationStatus Application
publicId 14413712
version 1
longName Clinical
context CRDC
workflowStatus RELEASED
registrationStatus Application
publicId 15020048
version 1
longName ICDC (Integrated Canine Data Commons)
context CRDC
workflowStatus RELEASED
registrationStatus Application
ClassificationSchemeItems
publicId 15020057
version 1
longName Clinical
context CRDC
workflowStatus RELEASED
registrationStatus Application
publicId 17012038
version 1
longName IDC (Imaging Data Commons)
context CRDC
workflowStatus RELEASED
registrationStatus Application
ClassificationSchemeItems
publicId 17012046
version 1
longName Diagnosis
context CRDC
workflowStatus RELEASED
registrationStatus Application
AlternateNames
name Primary Diagnosis
type CRDC Alt Name
context CRDC
name primary_diagnosis
type GC Alt Name
context CRDC
name primary_diagnosis_disease_group
type CTDC Alt Name
context CRDC
name diagnosis
type CTDC Table
context CRDC
name Primary Diagnosis
type TCIA Alt Name
context CIP
name disease_type
type GDC Alt Name
context GDC
name primary_diagnosis
type GDC Alt Name
context GDC
name primary_diagnosis
type IDC Alt Name
context CRDC
ReferenceDocuments
documentName PQT
documentText Primary Diagnosis
documentType Preferred Question Text
url
context CRDC
documentName CRDC Instruction
documentText Any disease or disorder concept code that is identified in the NCI Thesaurus hierarchy tree under the Disease or Diagnosis (C2991) branch.
documentType Instructions
url https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C2991
context CRDC
documentName CRDC SDO Reference
documentText Disease or Disorder Hierarchy C2991
documentType REFERENCE
url https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C2991
context CRDC
documentName CRDC Example
documentText Multiple Myeloma (C3242)
documentType EXAMPLE
url
context CRDC
apiResponse
type S