DataElement
publicId 14742451
version 1
longName Disease Progression Or Recurrence Type
shortName 13529781v1.00:6134062v2.00
definition The text term used to describe the type of worsening or reemergence of disease over time.
context CRDC
origin CRDC:Cancer Research Data Commons
workflowStatus RELEASED
registrationStatus Standard
latestVersionIndicator Yes
beginDate 2024-02-07
endDate
changeDescription
administrativeNotes 5/22/25 Added alt name, alt def, per June 2025 GDC DD. sl; 5/16/24 Corrected typo in def. mr; 4/23/24 Released per CRDC DSS SN CADSR0003632. mr; 2/7/24 Created per CRDC submission template. This CDE shares DEC with Prog or Rec Indicator CDE 13529783. Used v2.0 of VD 6134062 to update PVs for CRDC but keep connection to GDC CDE previously used by nodes. mr
unresolvedIssues
deletedIndicator No
createdBy COLBERTM
dateCreated 2024-02-07
modifiedBy SLAUER
dateModified 2025-05-22
DataElementConcept
publicId 13529781
version 1
longName Disease or Disorder Progression Or Recurrence
shortName 2404658v1.00:13529780v1.00
definition Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function.:A process that manifests as the worsening of a disease over time._An article used to connect words, phrases, or clauses representing alternatives; used to connect alternative terms for the same thing; used in correlation; used to correct or rephrase what was previously said; otherwise._The reemergence of a neoplasm after a period of remission.
context CRDC
origin CDS:Cancer Data Service
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2023-05-08
endDate
changeDescription
administrativeNotes 5/17/23 changed origin to CDS. BF; 5/8/23 Created per CDS metadata template. mr
unresolvedIssues
deletedIndicator No
createdBy COLBERTM
dateCreated 2023-05-08
modifiedBy SOKKERL
dateModified 2024-03-06
ObjectClass
publicId 2404658
version 1
longName Diseases and Disorders
shortName C2991
definition A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.
context NCIP
origin NCI Thesaurus
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2005-09-09
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy PWEST
dateCreated 2005-09-09
modifiedBy ONEDATA
dateModified 2005-09-09
Concepts
longName Disease or Disorder
conceptCode C2991
definition Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function.
evsSource NCI_CONCEPT_CODE
primaryIndicator Yes
displayOrder 0
Property
publicId 13529780
version 1
longName Disease Progression Or Recurrent Neoplasm
shortName C17747:C37998:C4798
definition A process that manifests as the worsening of a disease over time._An article used to connect words, phrases, or clauses representing alternatives; used to connect alternative terms for the same thing; used in correlation; used to correct or rephrase what was previously said; otherwise._The reemergence of a neoplasm after a period of remission.
context NCIP
origin
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2023-05-08
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy COLBERTM
dateCreated 2023-05-08
modifiedBy COLBERTM
dateModified 2023-05-08
Concepts
longName Disease Progression
conceptCode C17747
definition A process that manifests as the worsening of a disease over time.
evsSource NCI_CONCEPT_CODE
primaryIndicator No
displayOrder 2
longName Or
conceptCode C37998
definition An article used to connect words, phrases, or clauses representing alternatives; used to connect alternative terms for the same thing; used in correlation; used to correct or rephrase what was previously said; otherwise.
evsSource NCI_CONCEPT_CODE
primaryIndicator No
displayOrder 1
longName Recurrent Neoplasm
conceptCode C4798
definition The reemergence of a neoplasm after a period of remission.
evsSource NCI_CONCEPT_CODE
primaryIndicator Yes
displayOrder 0
ConceptualDomain
publicId 2435018
version 1
longName Clinical or Research Activity
shortName C16203
definition Any specific activity undertaken during the course of a clinical study or research protocol.
context NCIP
origin NCI Thesaurus
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2005-12-06
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy CURTIST
dateCreated 2005-12-06
modifiedBy SBR
dateModified 2006-12-20
ValueDomain
publicId 6134062
version 2
longName Disease Type
shortName 6134062v2.00
definition Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function._Something distinguishable as an identifiable class based on common qualities.
context CRDC
type Enumerated
dataType CHARACTER
minLength
maxLength 25
minValue
maxValue
decimalPlace
origin GDC:NCI Genomic Data Commons
workflowStatus RELEASED
registrationStatus Qualified
latestVersionIndicator Yes
beginDate 2018-03-15
endDate
changeDescription Created for caDSR Requests Q12018 Dictionary Updates for Review (supplement) 3.15.18 mc Confirmed list (added Biochemical to match GDC) and released VD after verification of the property in the GDC data dictionary. 8/24/20 MRC
administrativeNotes 2/7/24 Edited PVs to align with RFC 41. Upd owner of v2.0 to CRDC. v2.0 concepts upd from Biochemical C25434 to Biochemical Evidence of Disease C165196 from Distant C25321:C3261 to Distant Metastasis C18206. mr; 10/6/23 Versioned to update semantics and PVs for reuse by CRDC. mr;
unresolvedIssues
deletedIndicator No
createdBy COLBERTM
dateCreated 2023-10-06
modifiedBy COLBERTM
dateModified 2024-04-23
PermissibleValues
publicId 9133117
value Not Reported
valueDescription Not Reported
origin
beginDate 2018-03-15
endDate
deletedIndicator No
createdBy COOPERM
dateCreated 2023-10-06
modifiedBy ONEDATA
dateModified 2023-10-06
ValueMeaning
publicId 2572578
version 1
longName Not Reported
shortName 2572578
definition Not provided or available.
context NCIP
origin
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2004-12-30
endDate
changeDescription 03/09/2011 - tc - Updated with concept code.
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy CAMPBELB
dateCreated 2004-12-30
modifiedBy JKNABLE
dateModified 2024-08-04
Concepts
longName Not Reported
conceptCode C43234
definition Not provided or available.
evsSource NCI_CONCEPT_CODE
primaryIndicator Yes
displayOrder 0
Designations
languageName ENGLISH
name Not Reported
type UML Value Name
context NCIP
id 9F532489-FDFF-CB64-E040-BB89AD434637
createdBy CBMUMLLOADERMC
dateCreated 2011-03-25
modifiedBy ONEDATA
dateModified 2011-03-25
languageName ENGLISH
name NOT REPORTED
type CDISC SDTM SBM Value
context NCIP
id 68541139-A737-0CF7-E053-F662850AE9A7
createdBy Denise Warzel
dateCreated 2018-03-26
modifiedBy ONEDATA
dateModified 2018-03-26
languageName ENGLISH
name Not Reported
type CCDI-Fed Alt Name
context Pediatric Cancer
id 1EE4B6E6-8055-01B1-E063-731AD00A595C
createdBy Janice Knable
dateCreated 2024-08-04
modifiedBy JKNABLE
dateModified 2024-08-04
publicId 9133118
value Unknown
valueDescription Unknown
origin
beginDate 2018-03-15
endDate
deletedIndicator No
createdBy COOPERM
dateCreated 2023-10-06
modifiedBy ONEDATA
dateModified 2023-10-06
ValueMeaning
publicId 3104212
version 1
longName Unknown
shortName 3104212v1.00
definition Not known, observed, recorded; or reported as unknown by the data contributor.
context NCIP
origin
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2010-06-01
endDate
changeDescription Concept annotated for UPitt/TCGA. Ylu, 01/30/2015.
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy REEVESD
dateCreated 2010-06-01
modifiedBy CLOHNES
dateModified 2025-07-08
Concepts
longName Unknown
conceptCode C17998
definition Not known, observed, recorded; or reported as unknown by the data contributor.
evsSource NCI_CONCEPT_CODE
primaryIndicator Yes
displayOrder 0
Designations
languageName ENGLISH
name LA4489-6
type LOINC_CODE
context ONC
id 32AA44E9-59D2-420B-E050-BB89AD434F40
createdBy Denise Warzel
dateCreated 2016-05-12
modifiedBy ONEDATA
dateModified 2016-05-12
languageName ENGLISH
name Unknown
type LOINC_NAME
context ONC
id 32AA44E9-59FD-420B-E050-BB89AD434F40
createdBy Denise Warzel
dateCreated 2016-05-12
modifiedBy ONEDATA
dateModified 2016-05-12
languageName ENGLISH
name Unknown or null
type Sentinel Name
context CDMH
id 72F686B3-1FEC-7C94-E053-F662850AFAFB
createdBy Gwen Hartley Deen
dateCreated 2018-08-08
modifiedBy ONEDATA
dateModified 2018-08-08
languageName ENGLISH
name Unknown
type PCORNet Name
context CDMH
id 714738AA-F735-5651-E053-F662850A0811
createdBy Gwen Hartley Deen
dateCreated 2018-07-18
modifiedBy DWARZEL
dateModified 2018-09-27
languageName ENGLISH
name Unknown: Could not be determined or unsure
type VM Alt Name
context OCCPR
id 8B84D352-5D7F-66BE-E053-F662850AC7DF
createdBy Janice Knable
dateCreated 2019-06-17
modifiedBy ONEDATA
dateModified 2019-06-17
languageName ENGLISH
name Unknown
type VM Alt Name
context COG
id D20533D1-873A-3C14-E053-4EBD850A6403
createdBy Linda Springer
dateCreated 2021-11-30
modifiedBy ONEDATA
dateModified 2021-11-30
languageName ENGLISH
name UN=Unknown
type PCORNet Name
context CDMH
id 0CCC4B9C-82C5-664F-E063-731AD00A1F3F
createdBy Gwen Deen
dateCreated 2023-12-18
modifiedBy GDEEN
dateModified 2023-12-18
languageName ENGLISH
name Unknown
type CRDC Alt Name
context CRDC
id 0F5457E1-397E-670D-E063-731AD00A0504
createdBy Bobbie Fincham
dateCreated 2024-01-19
modifiedBy FINCHAMB
dateModified 2024-01-19
languageName ENGLISH
name UN=Unknown
type VM Alt Name
context CDMH
id 37CAC274-C87B-27CB-E063-731AD00AD063
createdBy Gwen Deen
dateCreated 2025-06-17
modifiedBy GDEEN
dateModified 2025-06-17
languageName ENGLISH
name Unknown
type VM Alt Name
context CCTG
id 396FB372-371F-167E-E063-731AD00A656D
createdBy Cassandra Lohnes
dateCreated 2025-07-08
modifiedBy CLOHNES
dateModified 2025-07-08
publicId 9133120
value Regional
valueDescription Regional Disease
origin
beginDate 2018-03-15
endDate
deletedIndicator No
createdBy COOPERM
dateCreated 2023-10-06
modifiedBy COLBERTM
dateModified 2024-02-07
ValueMeaning
publicId 2971661
version 1
longName Regional Disease
shortName 2971661
definition A disease or condition that extends beyond the site and spreads into adjacent tissues and regional lymph nodes.
context NCIP
origin
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2009-12-21
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy REEVESD
dateCreated 2009-12-21
modifiedBy COLBERTM
dateModified 2023-09-01
Concepts
longName Regional Disease
conceptCode C41844
definition A disease or condition that extends beyond the site of origin and spreads into adjacent tissues and regional lymph nodes.
evsSource NCI_CONCEPT_CODE
primaryIndicator Yes
displayOrder 0
Designations
languageName ENGLISH
name Regional
type CRDC Alt Name
context CRDC
id 044EFBC3-1E7E-40AE-E063-731AD00A6F3B
createdBy Maureen Ryan
dateCreated 2023-09-01
modifiedBy COLBERTM
dateModified 2023-09-01
publicId 9133121
value Local
valueDescription Localized Disease
origin
beginDate 2018-03-15
endDate
deletedIndicator No
createdBy COOPERM
dateCreated 2023-10-06
modifiedBy COLBERTM
dateModified 2024-02-12
ValueMeaning
publicId 3461432
version 1
longName Localized Disease
shortName 3461432
definition A disease that is confined to a specific organ or tissue and has not spread to other anatomic sites.
context NCIP
origin
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2012-05-15
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy COOPERM
dateCreated 2012-05-15
modifiedBy COLBERTM
dateModified 2025-08-19
Concepts
longName Localized Disease
conceptCode C36162
definition A disease that is confined to a specific organ or tissue and has not spread to other anatomic sites.
evsSource NCI_CONCEPT_CODE
primaryIndicator Yes
displayOrder 0
Designations
languageName ENGLISH
name Local
type CRDC Alt Name
context CRDC
id 044EF89C-3BD8-404C-E063-731AD00A46FD
createdBy Maureen Ryan
dateCreated 2023-09-01
modifiedBy COLBERTM
dateModified 2023-09-01
languageName ENGLISH
name Localized
type RCI Alt Name
context Pediatric Cancer
id 3CBB9EA2-59BC-1CE4-E063-731AD00A1AE2
createdBy Maureen Ryan
dateCreated 2025-08-19
modifiedBy COLBERTM
dateModified 2025-08-19
publicId 9133123
value Biochemical
valueDescription
origin
beginDate 2023-10-06
endDate
deletedIndicator No
createdBy COLBERTM
dateCreated 2023-10-06
modifiedBy COLBERTM
dateModified 2024-02-07
ValueMeaning
publicId 14527469
version 1
longName Biochemical Evidence of Disease
shortName 14527469v1.00
definition An indication that biochemical markers of a disease are present.
context NCIP
origin
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2023-10-06
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy COLBERTM
dateCreated 2023-10-06
modifiedBy COLBERTM
dateModified 2023-10-06
Concepts
longName Biochemical Evidence of Disease
conceptCode C165196
definition An indication that biochemical markers of a disease are present.
evsSource NCI_CONCEPT_CODE
primaryIndicator Yes
displayOrder 0
Designations
languageName ENGLISH
name Biochemical
type CRDC Alt Name
context CRDC
id 07109EFB-3E60-60BC-E063-731AD00A42B4
createdBy Maureen Ryan
dateCreated 2023-10-06
modifiedBy COLBERTM
dateModified 2023-10-06
publicId 9133124
value Distant
valueDescription
origin
beginDate 2023-10-06
endDate
deletedIndicator No
createdBy COLBERTM
dateCreated 2023-10-06
modifiedBy COLBERTM
dateModified 2024-02-07
ValueMeaning
publicId 5627051
version 1
longName Distant Metastasis
shortName 5627051
definition A biological process that involves the transfer and growth of cancer cells from the site of the primary tumor. Relocation of malignant cells during metastasis can be restricted to movement within a specific tissue/organ or may entail migration to a distal locus within the body. This phenotype is a characteristic of all malignant tumors.
context NCIP
origin
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2017-01-12
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy KUMMEROA
dateCreated 2017-01-12
modifiedBy COLBERTM
dateModified 2023-09-01
Concepts
longName Distant Metastasis
conceptCode C18206
definition A biological process that involves the transfer and growth of cancer cells from the site of the primary tumor. Relocation of malignant cells during metastasis can be restricted to movement within a specific tissue/organ or may entail migration to a distal locus within the body. This phenotype is a characteristic of all malignant tumors.
evsSource NCI_CONCEPT_CODE
primaryIndicator Yes
displayOrder 0
Designations
languageName ENGLISH
name Distant
type CRDC Alt Name
context CRDC
id 044E281F-638F-0DFC-E063-731AD00A1A13
createdBy Maureen Ryan
dateCreated 2023-09-01
modifiedBy COLBERTM
dateModified 2023-09-01
publicId 9156908
value Locoregional
valueDescription
origin
beginDate 2024-04-02
endDate
deletedIndicator No
createdBy COLBERTM
dateCreated 2024-04-02
modifiedBy COLBERTM
dateModified 2024-04-02
ValueMeaning
publicId 14880672
version 1
longName Locoregional Disease
shortName 14880672v1.00
definition A disease that occurs within a specific organ or tissue and extends into adjacent areas including lymph nodes.
context NCIP
origin
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2024-04-02
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy COLBERTM
dateCreated 2024-04-02
modifiedBy COLBERTM
dateModified 2024-04-02
Concepts
longName SLC22A5 wt Allele
conceptCode C207902
definition Human SLC22A5 wild-type allele is located in the vicinity of 5q31.1 and is approximately 26 kb in length. This allele, which encodes organic cation/carnitine transporter 2 protein, is involved in both organic cation transport and sodium-dependent carnitine uptake. Mutations in the gene are associated with primary carnitine deficiency.
evsSource NCI_CONCEPT_CODE
primaryIndicator Yes
displayOrder 0
ConceptualDomain
publicId 2008549
version 1
longName Involvement and Extent of Disease
shortName INV_AND_EXT_OF_DZ
definition indication of the presence and extent of disease.
context CTEP
origin
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2002-12-19
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy MSUPLEY
dateCreated 2002-12-19
modifiedBy SBR
dateModified 2003-10-29
RepresentationTerm
publicId 2789686
version 1
longName Disease or Disorder Type
shortName C2991:C25284
definition Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function.:Type; a subdivision of a particular kind of thing.
context NCIP
origin
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2008-09-29
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy LEATHERJ
dateCreated 2008-09-29
modifiedBy ONEDATA
dateModified 2008-09-29
Concepts
longName Disease or Disorder
conceptCode C2991
definition Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function.
evsSource NCI_CONCEPT_CODE
primaryIndicator No
displayOrder 1
longName Type
conceptCode C25284
definition Something distinguishable as an identifiable class based on common qualities.
evsSource NCI_CONCEPT_CODE
primaryIndicator Yes
displayOrder 0
ClassificationSchemes
publicId 10429357
version 1
longName GDC (Genomic Data Commons)
context CRDC
workflowStatus DRAFT NEW
registrationStatus Application
ClassificationSchemeItems
publicId 14506028
version 1
longName Candidate New GDC CDEs
context CRDC
workflowStatus DRAFT NEW
registrationStatus Application
publicId 10466051
version 1
longName All CRDC Standard CDEs
context CRDC
workflowStatus RELEASED
registrationStatus Application
ClassificationSchemeItems
publicId 10466054
version 1
longName Diagnosis
context CRDC
workflowStatus RELEASED
registrationStatus Application
AlternateNames
name Disease Progression or Recurrence Type
type CRDC Alt Name
context CRDC
name progression_or_recurrence_type
type GDC Alt Name
context GDC
ReferenceDocuments
documentName PQT
documentText Progression or Recurrence Type
documentType Preferred Question Text
url
context CRDC
apiResponse
type S