DataElement
publicId 11527735
version 2
longName Molecular Analysis Sequencing Library Read Layout Type
shortName 11527732v2.00:11527734v2.00
definition The read strategy or method that was used for sequencing and analysis of a nucleotide library.
context CRDC
origin CDS:Cancer Data Service
workflowStatus DRAFT MOD
registrationStatus Application
latestVersionIndicator Yes
beginDate 2022-11-03
endDate
changeDescription
administrativeNotes 6/16/26 Added CTDC alt name, CSI. mr; 6/9/26 Versioned to 2.0 to delete Single-indexed C165444 PV and replace with new concept for Single-End C227518, and to align with Code Map OCs. mr; 2/24/26 Added CIDC alts, CSI. mr; 12/18/25 added "Long Read" (new concept C223895) per SN 5794 for HTAN data submission to GC. jk; 2/20/24 AI released per SME/Amanda Bell approval. ls; 5/16/23 changed origin to CDS. BF; 1/19/23 Added CDS alt def, ref doc EXAMPLE; removed general CDS CSI, added CDS|Sequencing CSI; per metadata template. mr 11/3/22 Created per CRDC CDS submission metatdata template. mr
unresolvedIssues
deletedIndicator No
createdBy COLBERTM
dateCreated 2026-06-09
modifiedBy COLBERTM
dateModified 2026-06-16
DataElementConcept
publicId 11527732
version 2
longName Molecular Analysis Sequencing Library Read Layout
shortName 2626369v1.00:11555666v1.00
definition A laboratory procedure that involves the study of tissues, cells, and fluids using techniques to analyze biologically active molecules, including nucleic acids, proteins, lipids and carbohydrates, for the identification of processes, characteristics and abnormalities at the molecular level.:Specifies what read strategy or method was used for sequencing and analysis of a nucleotide library.
context CRDC
origin CDS:Cancer Data Service
workflowStatus DRAFT MOD
registrationStatus Application
latestVersionIndicator Yes
beginDate 2022-11-03
endDate
changeDescription
administrativeNotes 6/9/26 Versioned to 2.0 to delete Single-indexed C165444 PV and replace with new concept for Single-End C227518 and to update OC for Code Map while CDE was being versioned. mr; 2/20/24 AI released per SME/Amanda Bell approval.ls; 5/17/23 changed origin to CDS. BF; 11/3/22 Created per CRDC CDS submission metatdata template. mr
unresolvedIssues
deletedIndicator No
createdBy COLBERTM
dateCreated 2026-06-09
modifiedBy COLBERTM
dateModified 2026-06-09
ObjectClass
publicId 2626369
version 1
longName Molecular Analysis
shortName C19770
definition Techniques for studying or analyzing the genetic composition and mechanisms of living organisms at the molecular level. May refer to the understanding and manipulation of genes (DNA).
context NCIP
origin NCI Thesaurus
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2007-04-13
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy ALAIS
dateCreated 2007-04-13
modifiedBy ONEDATA
dateModified 2007-04-13
Concepts
longName Molecular Analysis
conceptCode C19770
definition A laboratory procedure that involves the study of tissues, cells, and fluids using techniques to analyze biologically active molecules, including nucleic acids, proteins, lipids and carbohydrates, for the identification of processes, characteristics and abnormalities at the molecular level.
evsSource NCI_CONCEPT_CODE
primaryIndicator Yes
displayOrder 0
Property
publicId 11555666
version 1
longName Sequencing Library Read Layout Indicator
shortName C175894
definition Specifies what read strategy or method was used for sequencing and analysis of a nucleotide library.
context NCIP
origin
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2022-11-06
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy JKNABLE
dateCreated 2022-11-06
modifiedBy JKNABLE
dateModified 2022-11-06
Concepts
longName Sequencing Library Read Layout Indicator
conceptCode C175894
definition Specifies what read strategy or method was used for sequencing and analysis of a nucleotide library.
evsSource NCI_CONCEPT_CODE
primaryIndicator Yes
displayOrder 0
ConceptualDomain
publicId 2435018
version 1
longName Clinical or Research Activity
shortName C16203
definition Any specific activity undertaken during the course of a clinical study or research protocol.
context NCIP
origin NCI Thesaurus
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2005-12-06
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy CURTIST
dateCreated 2005-12-06
modifiedBy SBR
dateModified 2006-12-20
ValueDomain
publicId 11527734
version 2
longName Sequencing Library Read Layout Type
shortName 11527734v2.00
definition The determination of the sequence of component residues in a macromolecule, e.g. amino acids in a protein or nucleotide bases in DNA/RNA or the computational analysis performed to determine the similarities between nonidentical proteins or molecules of DNA or RNA._Something distinguishable as an identifiable class based on common qualities._Specifies what read strategy or method was used for sequencing and analysis of a nucleotide library.
context CRDC
type Enumerated
dataType CHARACTER
minLength
maxLength 50
minValue
maxValue
decimalPlace
origin CDS:Cancer Data Service
workflowStatus DRAFT MOD
registrationStatus Application
latestVersionIndicator Yes
beginDate 2022-11-03
endDate
changeDescription
administrativeNotes 6/9/26 Versioned to 2.0 to delete Single-indexed C165444 PV and replace with new concept for Single-End C227518. mr; 12/18/25 added "Long Read" (new concept C223895) per SN 5794 for HTAN data submission to GC. jk; 2/20/24 AI released per SME/Amanda Bell approval.ls; 5/17/23 changed origin to CDS. BF; 11/8/22 Added max len, changed datatype to Character. mr; 11/3/22 Created per CRDC CDS submission metadata template. mr
unresolvedIssues
deletedIndicator No
createdBy COLBERTM
dateCreated 2026-06-09
modifiedBy COLBERTM
dateModified 2026-06-09
PermissibleValues
publicId 9272688
value Paired-End
valueDescription
origin
beginDate 2022-11-03
endDate
deletedIndicator No
createdBy COLBERTM
dateCreated 2026-06-09
modifiedBy JKNABLE
dateModified 2026-06-09
ValueMeaning
publicId 11529032
version 1
longName Paired-End Sequencing
shortName 11529032v1.00
definition A DNA sequencing strategy where a single read is initiated from each end of a DNA fragment.
context NCIP
origin
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2022-11-03
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy COLBERTM
dateCreated 2022-11-03
modifiedBy COLBERTM
dateModified 2026-02-27
Concepts
longName Paired-End Sequencing
conceptCode C150423
definition A DNA sequencing strategy where a single read is initiated from each end of a DNA fragment.
evsSource NCI_CONCEPT_CODE
primaryIndicator Yes
displayOrder 0
Designations
languageName ENGLISH
name Paired
type CIDC Alt Name
context CRDC
id 4BD39F4B-04AD-09D1-E063-731AD00AFCD0
createdBy Maureen Ryan
dateCreated 2026-02-24
modifiedBy COLBERTM
dateModified 2026-02-27
publicId 9272690
value Long Read
valueDescription
origin
beginDate 2025-12-18
endDate
deletedIndicator No
createdBy JKNABLE
dateCreated 2026-06-09
modifiedBy JKNABLE
dateModified 2026-06-09
ValueMeaning
publicId 16861164
version 1
longName Long Read Sequencing
shortName 16861164v1.00
definition The sequencing of long, continuous DNA fragments.
context NCIP
origin
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2025-12-18
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy JKNABLE
dateCreated 2025-12-18
modifiedBy JKNABLE
dateModified 2025-12-18
Concepts
longName Long Read Sequencing
conceptCode C223895
definition The sequencing of long, continuous DNA fragments.
evsSource NCI_CONCEPT_CODE
primaryIndicator Yes
displayOrder 0
publicId 9272728
value Single-End
valueDescription
origin
beginDate 2026-06-09
endDate
deletedIndicator No
createdBy COLBERTM
dateCreated 2026-06-09
modifiedBy COLBERTM
dateModified 2026-06-09
ValueMeaning
publicId 17348845
version 1
longName Single-End Sequencing
shortName 17348845v1.00
definition A DNA sequencing strategy where a single read is initiated from a single end of a DNA fragment.
context NCIP
origin
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2026-06-09
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy COLBERTM
dateCreated 2026-06-09
modifiedBy COLBERTM
dateModified 2026-06-09
Concepts
longName Single-End Sequencing
conceptCode C227518
definition A DNA sequencing strategy where a single read is initiated from a single end of a DNA fragment.
evsSource NCI_CONCEPT_CODE
primaryIndicator Yes
displayOrder 0
Designations
languageName ENGLISH
name Single
type CIDC Alt Name
context CRDC
id 53D84D3B-C6F9-7D96-E063-731AD00A4AA9
createdBy Maureen Ryan
dateCreated 2026-06-09
modifiedBy COLBERTM
dateModified 2026-06-09
ConceptualDomain
publicId 2435018
version 1
longName Clinical or Research Activity
shortName C16203
definition Any specific activity undertaken during the course of a clinical study or research protocol.
context NCIP
origin NCI Thesaurus
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2005-12-06
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy CURTIST
dateCreated 2005-12-06
modifiedBy SBR
dateModified 2006-12-20
RepresentationTerm
publicId 11555665
version 1
longName Sequencing Library Read Layout Indicator Type
shortName 11555665v1.00
definition Specifies what read strategy or method was used for sequencing and analysis of a nucleotide library._Something distinguishable as an identifiable class based on common qualities.
context NCIP
origin
workflowStatus RELEASED
registrationStatus Application
latestVersionIndicator Yes
beginDate 2022-11-06
endDate
changeDescription
administrativeNotes
unresolvedIssues
deletedIndicator No
createdBy JKNABLE
dateCreated 2022-11-06
modifiedBy JKNABLE
dateModified 2022-11-06
Concepts
longName Sequencing Library Read Layout Indicator
conceptCode C175894
definition Specifies what read strategy or method was used for sequencing and analysis of a nucleotide library.
evsSource NCI_CONCEPT_CODE
primaryIndicator No
displayOrder 1
longName Type
conceptCode C25284
definition Something distinguishable as an identifiable class based on common qualities.
evsSource NCI_CONCEPT_CODE
primaryIndicator Yes
displayOrder 0
ClassificationSchemes
publicId 8064110
version 1
longName GC (General Commons)
context CRDC
workflowStatus RELEASED
registrationStatus Application
ClassificationSchemeItems
publicId 12177495
version 1
longName Sequencing
context CRDC
workflowStatus RELEASED
registrationStatus Application
publicId 11518160
version 1
longName CTDC (Clinical and Translational Data Commons)
context CRDC
workflowStatus RELEASED
registrationStatus Application
ClassificationSchemeItems
publicId 14413707
version 1
longName CTDC Model
context CRDC
workflowStatus RELEASED
registrationStatus Application
publicId 14413713
version 1
longName Biospecimen
context CRDC
workflowStatus RELEASED
registrationStatus Application
publicId 17002960
version 1
longName Assay
context CRDC
workflowStatus RELEASED
registrationStatus Application
publicId 13574489
version 1
longName CCDI (Childhood Cancer Data Initiative)
context Pediatric Cancer
workflowStatus RELEASED
registrationStatus Application
ClassificationSchemeItems
publicId 13594094
version 1
longName Sequencing
context Pediatric Cancer
workflowStatus RELEASED
registrationStatus Application
publicId 13594223
version 1
longName Sequencing File
context Pediatric Cancer
workflowStatus RELEASED
registrationStatus Application
publicId 13594225
version 1
longName Single Cell Sequencing File
context Pediatric Cancer
workflowStatus RELEASED
registrationStatus Application
AlternateNames
name sequencing_file
type CCDI Table
context Pediatric Cancer
name library_layout
type CCDI Alt Name
context Pediatric Cancer
name library_layout
type GC Alt Name
context CRDC
name paired_end_reads
type CIDC Alt Name
context CRDC
name paired_end_sequencing
type CTDC Alt Name
context CRDC
ReferenceDocuments
documentName PQT
documentText Read Layout
documentType Preferred Question Text
url
context CRDC
documentName CDS
documentText paired-end
documentType EXAMPLE
url
context CRDC
apiResponse
type S